Cast
- Numbuh 1 as Mr. Happy
- Numbuh 2 as Mr. Clever
- Numbuh 3
- Numbuh 4 as Mr. Small
- Numbuh 5
- Numbuh 362 as Little Miss Brainy
- Numbuh 60 as Mr. Strong
- Numbuh 10 as Little Miss Magic
- Joe Balooka as Mr. Worry
- Trevor as Mr. Busy
- The Kid as Mr. Tickle
- Numbuh 1-Love as Mr. Daydream
- Chad Dickson
- James Nixon McGarfield as Mr. Uppity
- Grandfather as Mr. Mean
- Father as Mr. Grumble
- Heinrich Von Marzipan as Mr. Mischief
- Cree Lincoln as Little Miss Naughty
- Mushi Sanban
- Numbuh 86 as Little Miss Bossy
- Buster Bunny (from Tiny Toon Adventures) as Mr. Nonsense
- Hamton J. Pig
- Babs Bunny
- Plucky Duck
- Furrball
- Shirley the Loon
- Fifi La Fume
- Ed (from Ed, Edd N Eddy) as Mr. Forgetful
- Double D
- Eddy (from Ed, Edd N Eddy) as Mr. Greedy
- Blossom
- Bubbles
- Buttercup
- Brick
- Boomer
- Butch
- (from Dexter's Laboratory) as Mr. Impossible