• Odie as Curious George
  • Roy as The Man with the Yellow Hat
  • Lenore as Georgina
  • Orson as Doctor Barker
  • Bo as The Zookeeper
  • Lanolin as Carol
  • Nermal as The Boy
  • Liz Wilson as Tthe Nurse
  • Booker as Steve
  • Sheldon as Charkie
  • Chloe as Betsy
  • Garfield as Door Man
  • Bobby Buddy Bear as Hundley
  • Jon Arbuckle as Chef Pisghetti
  • Arlene as Netti
  • Billy Buddy Bear as Gnocchi
  • Bertie Buddy Bear as Bill
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