Cast
- Mr. Small (from The Mr. Men Show) as Mega Man
- Mr. Bounce (from The Mr. Men Show) as Rush
- Mr. Nosey (from The Mr. Men Show) as Proto Man
- Mr. Strong
- Mr. Bump (from The Mr. Men Show) as Cut Man
- Little Miss Chatterbox (from The Mr. Men Show) as Splash Woman
- Little Miss Bossy
- Bowser (from Mario) as Dr. Wily
- Yakko (from Animaniacs) as Ice Man
- (from Animaniacs) as Fire Man
- Plucky Duck (from Tiny Toon Adventures) as Bomb Man
- Buster Bunny
- (from Sonic) as Metal Man
- (from Sonic) as Heat Man
- (from SML) as Flash Man
- Tails (from Sonic) as Bubble Man
- Mr. Daydream
- Mr. Muddle
- (from SML) as Crash Man
- (from Tiny Toon Adventures) as Quick Man