Cast[]
- Clyde as Yakko
- Pinky as Wakko
- Sue as Dot
- Rouge (from Sonic) as Hello Nurse
- Mezmeron as Dr. ScratchnSniff
- Dr. Robotnik (from Adventures of Sonic the Hedgehog) as Mr. Plotz
- King Koopa (from Super Mario World) as Ralph
- PJ as Pinky
- Pac-Man as Brain
- Scratch (from Adventures of Sonic the Hedgehog) as Squit
- Grounder (from Adventures of Sonic the Hedgehog) as Bobby
- Coconuts (from Adventures of Sonic the Hedgehog) as Pesto
- Kootie Pie (from Super Mario World) as Slappy Squirrel
- Inky as Skippy Squirrel
- Breezie (from Sonic) as Rita
- Blinky as Runt