• Sam Brenner as Toby Thompson
  • President Will Cooper as Mr. Bill Thompson
  • First Lady Jane Cooper as Mrs. Jane Thompson
  • Eddie Plant as Loogie
  • Ludlow Lamonsoff as Lug
  • Admiral James Porter as Laser
  • Lieutenant Colonel Violet Van Patten as Stacy Thompson
  • Mickey Lamonsoff as Colbert "Cole" Black
  • Lady Lisa as Helvetica Black
  • Donkey Kong as The Wishing Rock
  • Pac-Man as The Greedy Selfish Booger
  • Q*Bert as John
  • Video Game Characters as Germs
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